I think reaction to a drug should be based on the character in question. You can use the coded echo to give you a starting point as to what the drug might make you feel, but it's up to you, the player, to decide exactly how crazy that little puff of smoke or snort up the nose might get you.
IRL I've done my fair share of drugs and seen alot of people do alot of them and if I've learned anything it's that you can never be quite sure how a particular person will act to a particular 'high'.
I've seen people snort a small line of coke and flip out, jabbering like an idiot and twitching and grinding their teeth. This is the generally accepted reaction to coke. It makes you skitz. However, when I do a bit it makes me feel gooey and relaxed. I don't like to talk, I don't like to grind my teeth, I only like to sit and watch, mebbe smoke a few cigarettes quietly.
Most people I've seen who smoke a hooter get lazy and smily, kinda goofy. I've seen people get melancholy or giggly-happy. I, on the other hand, do not fit into the stereotypical 'pothead' mold. I like to get high and read my book or write a story over at NS, or if I'm feeling particularly energetic, to work out a bit. I've been getting high regularly for almost ten years and I can honesly say that not one single time in this time have I slapped on a stupid, hazy-eyed goofy ass grin and wandered off, mumbling about the killer new emo tunez I just heard or looking for cupcakes. I just don't fit into the mold and I never will and I refuse to believe that any of you, save for possibly staff, or a vague echo sets the tone for my character's spice induced episodes. They may give a starting point, but *I* decide where it goes from there.
I could go on, but I won't. Broad generalizations about 'that pot-head' or 'this rinth-rat spice-fiend' don't float, RL or Zalanthas.
Scowling fiercely up at the blazed-out, hairy-backed human man that perches on the bartop, the uncomprimising, hard-ass Nakki templar says, in sirihish:
"NO MUTHAFUCKA! You won't be drawn and quartered for smoking spice, it's not smoking spice the "RIGHT WAY" that you will be punished for. Prepare yourself for the Fury of the Highlord!"
Covering his bare crotch with one hand while waving his spice-pipe in the other, the blazed-out, furry-backed human man says, in sirihish:
"Damn! I knew I should have acted 'euphoric'. Damn it all! Now I will pay the ultimate price..."